[HTML][HTML] Proximity extension assay in combination with next-generation sequencing for high-throughput proteome-wide analysis
L Wik, N Nordberg, J Broberg, J Björkesten… - Molecular & Cellular …, 2021 - ASBMB
Understanding the dynamics of the human proteome is crucial for developing biomarkers to
be used as measurable indicators for disease severity and progression, patient stratification,
and drug development. The Proximity Extension Assay (PEA) is a technology that translates
protein information into actionable knowledge by linking protein-specific antibodies to DNA-
encoded tags. In this report we demonstrate how we have combined the unique PEA
technology with an innovative and automated sample preparation and high-throughput …
be used as measurable indicators for disease severity and progression, patient stratification,
and drug development. The Proximity Extension Assay (PEA) is a technology that translates
protein information into actionable knowledge by linking protein-specific antibodies to DNA-
encoded tags. In this report we demonstrate how we have combined the unique PEA
technology with an innovative and automated sample preparation and high-throughput …