Dyslipidemia and inflammation are well known causal risk factors the development of
atherosclerosis. The interplay between lipid metabolism and inflammation at multiple levels
in metabolic active tissues may exacerbate the development of atherosclerosis, and will be
discussed in this review. Cholesterol, fatty acids and modified lipids can directly activate
inflammatory pathways. In addition, circulating (modified) lipoproteins modulate the activity
of leukocytes. Vice versa, proinflammatory signaling (ie cytokines) in pre-clinical models …