Trends in the prevalence of ketoacidosis at diabetes diagnosis: the SEARCH for diabetes in youth study
OBJECTIVE: To estimate temporal changes in the prevalence of diabetic ketoacidosis (DKA)
at diagnosis of type 1 or type 2 diabetes in youth and to explore factors associated with its
occurrence. METHODS: Five centers identified incident cases of diabetes among youth
aged 0 to 19 years starting in 2002. DKA presence was defined as a bicarbonate level< 15
mmol/L and/or a pH< 7.25 (venous) or< 7.30 (arterial or capillary) or mention of DKA in the
medical records. We assessed trends in the prevalence of DKA over 3 time periods (2002 …
at diagnosis of type 1 or type 2 diabetes in youth and to explore factors associated with its
occurrence. METHODS: Five centers identified incident cases of diabetes among youth
aged 0 to 19 years starting in 2002. DKA presence was defined as a bicarbonate level< 15
mmol/L and/or a pH< 7.25 (venous) or< 7.30 (arterial or capillary) or mention of DKA in the
medical records. We assessed trends in the prevalence of DKA over 3 time periods (2002 …