[HTML][HTML] Cardiovascular Neurohormonal Regulation: Exacerbated effects of prorenin on hypothalamic magnocellular neuronal activity and vasopressin plasma levels …
Accumulating evidence supports that the brain renin-angiotensin system (RAS), including
prorenin (PR) and its receptor (PRR), two newly discovered RAS players, contribute to
sympathoexcitation in salt-sensitive hypertension. Still, whether PR also contributed to
elevated circulating levels of neurohormones such as vasopressin (VP) during salt-sensitive
hypertension, and if so, what are the precise underlying mechanisms, remains to be
determined. To address these questions, we obtained patch-clamp recordings from …
prorenin (PR) and its receptor (PRR), two newly discovered RAS players, contribute to
sympathoexcitation in salt-sensitive hypertension. Still, whether PR also contributed to
elevated circulating levels of neurohormones such as vasopressin (VP) during salt-sensitive
hypertension, and if so, what are the precise underlying mechanisms, remains to be
determined. To address these questions, we obtained patch-clamp recordings from …
Exacerbated effects of prorenin on hypothalamic magnocellular neuronal activity and vasopressin plasma levels during salt-sensitive hypertension
Accumulating evidence supports that the brain renin-angiotensin system (RAS), including
prorenin (PR) and its receptor (PRR), two newly discovered RAS players, contribute to
sympathoexcitation in salt-sensitive hypertension. Still, whether PR also contributed to
elevated circulating levels of neurohormones such as vasopressin (VP) during salt-sensitive
hypertension, and if so, what are the precise underlying mechanisms, remains to be
determined. To address these questions, we obtained patch-clamp recordings from …
prorenin (PR) and its receptor (PRR), two newly discovered RAS players, contribute to
sympathoexcitation in salt-sensitive hypertension. Still, whether PR also contributed to
elevated circulating levels of neurohormones such as vasopressin (VP) during salt-sensitive
hypertension, and if so, what are the precise underlying mechanisms, remains to be
determined. To address these questions, we obtained patch-clamp recordings from …