The glomerulus, the filtering unit of the kidney, is a unique bundle of capillaries lined by
delicate fenestrated endothelia, a complex mesh of proteins that serve as the glomerular
basement membrane and specialized visceral epithelial cells that form the slit diaphragms
between interdigitating foot processes. Taken together, this arrangement allows continuous
filtration of the plasma volume. The dynamic physical forces that determine the single
nephron glomerular filtration are considered. In addition, new insights into the cellular and …