[HTML][HTML] The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to
a certain stage of development, scientists have attempted to replicate scarless wound
healing in adults with little success. While the extracellular matrix (ECM), fibroblasts, and
inflammatory mediators have been historically investigated as separate branches of biology,
it has become increasingly necessary to consider them as parts of a complex and tightly …
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to
a certain stage of development, scientists have attempted to replicate scarless wound
healing in adults with little success. While the extracellular matrix (ECM), fibroblasts, and
inflammatory mediators have been historically investigated as separate branches of biology,
it has become increasingly necessary to consider them as parts of a complex and tightly …