[HTML][HTML] Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease
Adipose tissue serves as a host reservoir for the protozoan Trypanosoma cruzi, the
causative organism in Chagas disease. Gap junctions interconnect cells of most tissues,
serving to synchronize cell activities including secretion in glandular tissue, and we have
previously demonstrated that gap junctions are altered in various tissues and cells infected
with T. cruzi. Herein, we examined the gap junction protein connexin 43 (Cx43) expression
in infected adipose tissues. Adipose tissue is the largest endocrine organ of the body and is …
causative organism in Chagas disease. Gap junctions interconnect cells of most tissues,
serving to synchronize cell activities including secretion in glandular tissue, and we have
previously demonstrated that gap junctions are altered in various tissues and cells infected
with T. cruzi. Herein, we examined the gap junction protein connexin 43 (Cx43) expression
in infected adipose tissues. Adipose tissue is the largest endocrine organ of the body and is …