Proton pump inhibitor use and the risk of chronic kidney disease
Importance Proton pump inhibitors (PPIs) are among the most commonly used drugs
worldwide and have been linked to acute interstitial nephritis. Less is known about the
association between PPI use and chronic kidney disease (CKD). Objective To quantify the
association between PPI use and incident CKD in a population-based cohort. Design,
Setting, and Participants In total, 10 482 participants in the Atherosclerosis Risk in
Communities study with an estimated glomerular filtration rate of at least 60 mL/min/1.73 m 2 …
worldwide and have been linked to acute interstitial nephritis. Less is known about the
association between PPI use and chronic kidney disease (CKD). Objective To quantify the
association between PPI use and incident CKD in a population-based cohort. Design,
Setting, and Participants In total, 10 482 participants in the Atherosclerosis Risk in
Communities study with an estimated glomerular filtration rate of at least 60 mL/min/1.73 m 2 …