Myopathy associated with HMG-CoA reductase inhibitors (statins): a series of 10 patients and review of the literature
PA McKelvie, X Dennett - Journal of Clinical Neuromuscular …, 2002 - journals.lww.com
Objective To examine the clinical profile of patients with myotoxicity due to HMG-CoA
reductase inhibitors and the pathological features in the biopsies. Design All patients
receiving HMG-CoA reductase inhibitors who underwent muscle biopsy at the State
Neuropathology Service, Melbourne, from October 2000 to September 2001 were identified,
and clinical questionnaires were completed by the referring doctor. Results Ten patients,
including 4 males and 6 females, aged 50 to 76 years (median, 69.5 y), were identified. Six …
reductase inhibitors and the pathological features in the biopsies. Design All patients
receiving HMG-CoA reductase inhibitors who underwent muscle biopsy at the State
Neuropathology Service, Melbourne, from October 2000 to September 2001 were identified,
and clinical questionnaires were completed by the referring doctor. Results Ten patients,
including 4 males and 6 females, aged 50 to 76 years (median, 69.5 y), were identified. Six …
