Focal epilepsy (FE) is one of the most common forms of adult epilepsy and is usually
regarded as a multifactorial disorder. Febrile seizures (FS) often appear during childhood in
a subtype of FE patients, ie with temporal lobe epilepsy (TLE) and hippocampal sclerosis
(HS). FS are the most common human convulsive event associated with fever. Genetic
evidences for FS have suggested a complex mode of inheritance. Until now, to investigate
genes at the genomic level, linkage analysis of familial forms and association studies have …