Activation of inflammatory and immune pathways may contribute to the development of
epilepsy. Dendritic cells (DCs), a heterogeneous group of professional antigen presenting
cells, can be detected in the brain under several inflammatory conditions. However, the
spatiotemporal distribution and origin of seizure-induced DCs accumulation in the brain
have not been explored yet. In the present study, we demonstrate the presence of CD11c-
positive DCs in the hippocampus, thalamus and temporal cortex following Li-pilocarpine …