[HTML][HTML] Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells

H Shindou, H Koso, J Sasaki, H Nakanishi… - Journal of Biological …, 2017 - ASBMB
Docosahexaenoic acid (DHA) has essential roles in photoreceptor cells in the retina and is
therefore crucial to healthy vision. Although the influence of dietary DHA on visual acuity is
well known and the retina has an abundance of DHA-containing phospholipids (PL-DHA),
the mechanisms associated with DHA's effects on visual function are unknown. We
previously identified lysophosphatidic acid acyltransferase 3 (LPAAT3) as a PL-DHA
biosynthetic enzyme. Here, using comprehensive phospholipid analyses and imaging mass …