Immune responses in mice and pigs after oral vaccination with rabies virus vectored Nipah disease vaccines
L Shuai, J Ge, Z Wen, J Wang, X Wang, Z Bu - Veterinary microbiology, 2020 - Elsevier
Nipah virus (NiV) is a re-emerging zoonotic pathogen that causes high mortality in humans
and pigs. Oral immunization in free-roaming animals is one of the most practical approaches
to prevent NiV pandemics. We previously generated a recombinant rabies viruses (RABV)
Evelyn-Rokitnicki-Abelseth (ERA) strain, rERAG 333E, which contains a mutation from
arginine to glutamic acid at residue 333 of glycoprotein (G 333E) and serves as an oral
vaccine for dog rabies. In this study, we generated two recombinant RABVs, rERAG …
and pigs. Oral immunization in free-roaming animals is one of the most practical approaches
to prevent NiV pandemics. We previously generated a recombinant rabies viruses (RABV)
Evelyn-Rokitnicki-Abelseth (ERA) strain, rERAG 333E, which contains a mutation from
arginine to glutamic acid at residue 333 of glycoprotein (G 333E) and serves as an oral
vaccine for dog rabies. In this study, we generated two recombinant RABVs, rERAG …
