[HTML][HTML] Multiple origins of extracellular DNA traps

E Ramos-Martínez, L Hernández-González… - Frontiers in …, 2021 - frontiersin.org
E Ramos-Martínez, L Hernández-González, I Ramos-Martinez, L Perez-Campos Mayoral
Frontiers in immunology, 2021frontiersin.org
Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms
present in protozoa, plants, and animals. In this review, we compare their similarities in
species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our
results are consistent with a process of evolutionary convergence in multicellular organisms
through the application of a congruency test. Furthermore, we discuss why multicellularity is
related to the presence of a mechanism initiating the formation of ETs.
Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs.
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