Association of primary and booster vaccination and prior infection with SARS-CoV-2 infection and severe COVID-19 outcomes
Importance Data about the association of COVID-19 vaccination and prior SARS-CoV-2
infection with risk of SARS-CoV-2 infection and severe COVID-19 outcomes may guide
prevention strategies. Objective To estimate the time-varying association of primary and
booster COVID-19 vaccination and prior SARS-CoV-2 infection with subsequent SARS-CoV-
2 infection, hospitalization, and death. Design, Setting, and Participants Cohort study of 10.6
million residents in North Carolina from March 2, 2020, through June 3, 2022. Exposures …
infection with risk of SARS-CoV-2 infection and severe COVID-19 outcomes may guide
prevention strategies. Objective To estimate the time-varying association of primary and
booster COVID-19 vaccination and prior SARS-CoV-2 infection with subsequent SARS-CoV-
2 infection, hospitalization, and death. Design, Setting, and Participants Cohort study of 10.6
million residents in North Carolina from March 2, 2020, through June 3, 2022. Exposures …
