[HTML][HTML] Bronchoalveolar lavage cell immunophenotyping facilitates diagnosis of lung allograft rejection

JR Greenland, NP Jewell, M Gottschall… - American Journal of …, 2014 - Elsevier
Supplementary methods to identify acute rejection and to distinguish rejection from infection
may improve clinical outcomes for lung allograft recipients. We hypothesized that distinct
bronchoalveolar lavage (BAL) cell profiles are associated with rejection and infection. We
retrospectively compared 2939 BAL cell counts and immunophenotypes against
concomitantly obtained transbronchial biopsies and microbiologic studies. We randomly
assigned 317 subjects to a derivation or validation cohort. BAL samples were classified into …