Association between increased plasma ceramides and chronic kidney disease in patients with and without ischemic heart disease

A Mantovani, G Lunardi, S Bonapace, C Dugo… - Diabetes & …, 2021 - Elsevier
Aim Plasma levels of certain ceramides are increased in patients with ischemic heart
disease (IHD). Many risk factors for IHD are also risk factors for chronic kidney disease
(CKD), but it is currently uncertain whether plasma ceramide levels are increased in patients
with CKD. Methods We measured six previously identified high-risk plasma ceramide
concentrations [Cer (d18: 1/16: 0), Cer (d18: 1/18: 0), Cer (d18: 1/20: 0), Cer (d18: 1/22: 0),
Cer (d18: 1/24: 0) and Cer (d18: 1/24: 1)] in 415 middle-aged individuals who attended our …