Placenta percreta and uterine rupture associated with prior whole body radiation therapy
ER Norwitz, HM Stern, H Grier, A Lee-Parritz - Obstetrics & Gynecology, 2001 - Elsevier
Background: Injury to reproductive organs including the uterus is a known complication of
ionizing radiation, but the risks to the mother and fetus during subsequent pregnancies are
not well defined. Case: A young woman with a remote history of whole body irradiation for
childhood leukemia had uterine rupture at 17 weeks' gestation. Pathologic examination of
the supracervical hysterectomy specimen revealed a posterior-fundal placenta percreta with
a diffusely thinned myometrium (1–6 mm). The clinicopathologic findings were consistent …
ionizing radiation, but the risks to the mother and fetus during subsequent pregnancies are
not well defined. Case: A young woman with a remote history of whole body irradiation for
childhood leukemia had uterine rupture at 17 weeks' gestation. Pathologic examination of
the supracervical hysterectomy specimen revealed a posterior-fundal placenta percreta with
a diffusely thinned myometrium (1–6 mm). The clinicopathologic findings were consistent …
